Open AccessAssociation of glutathione S-transferase M1 polymorphisms in the colorectal cancer risk
Author(s) -
Min Huang,
Yan Zeng,
Fen Zhao,
Ying Huang
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_446_16
Subject(s) - odds ratio , medicine , colorectal cancer , genotype , confidence interval , subgroup analysis , glutathione s transferase , meta analysis , gastroenterology , case control study , oncology , glutathione , cancer , biology , genetics , gene , enzyme , biochemistry
The glutathione S-transferase M1 (GSTM1) as a member of phase II detoxification enzymes is expressed in many tissues and plays a critical role in preventing the occurrence of cancer. Published data regarding the associations between the GSTM1 polymorphism and colorectal cancer (CRC) risk are inconclusive.