Open AccessFrequency and risk factors of bleomycin-induced pulmonary toxicity in South Indian patients with germ-cell tumors
Author(s) -
Dimpal N Thakkar,
Kesavan Ramasamy,
Subathra Adithan,
Sandhiya Selvarajan,
Biswajit Dubashi
Publication year - 2021
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_348_19
Subject(s) - regimen , bleomycin , medicine , germ cell tumors , etoposide , pulmonary toxicity , toxicity , population , gastroenterology , surgery , chemotherapy , environmental health
Bleomycin, etoposide, and cisplatin (BEP) regimen is the standard treatment for germ-cell tumors (GCTs). Bleomycin-induced pulmonary toxicity (BPT) is fatal and dose-limiting toxicity associated with this regimen. In this study, we aimed to identify the frequency and risk factors of BPT in South Indian GCT patients receiving BEP regimen.