Open AccessEvaluation of antiangiogenic and antiproliferative potential of ethanolic extracts of Andrographis echioides using in vitro and in ovo assays
Author(s) -
Karthiga Muralidharan,
Punnagai Kumaravelu,
Darling Chellathai David
Publication year - 2021
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_325_19
Subject(s) - mtt assay , chorioallantoic membrane , pharmacology , in ovo , chemistry , traditional medicine , ic50 , thalidomide , andrographolide , in vitro , medicine , biology , biochemistry , immunology , embryo , multiple myeloma , microbiology and biotechnology
Andrographis echioides is a prevalently used medicinal herb in South Asian countries. Scientific researches with the extracts of A. echioides revealed its antipyretic, anti-inflammatory, antimicrobial, ulceroprotective, and hepatoprotective properties. This study was done to elucidate antiproliferative and antiangiogenic potential of ethanolic extracts of A. echioides (EEAE) by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-tetrazolium bromide (MTT) assay and chorioallantoic membrane (CAM) assay.