Open AccessPlasma fatty acids composition and estimated delta desaturases activity in women with breast cancer
Author(s) -
A Preethika,
Suchetha Kumari N,
Jyothi Shetty,
Vijith Shetty
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_288_19
Subject(s) - linoleic acid , breast cancer , medicine , enzyme , endocrinology , fatty acid synthase , fatty acid , chemistry , biology , cancer , biochemistry
Fatty acids (FAs) are the vital constituents of membrane structures. De novo synthesis of FAs includes an enzymatic complex of FA synthase and delta desaturases. These enzymes are overexpressed in tumors, and inhibition of these enzymes is gaining interest. Our aim was to determine if delta desaturase activities are altered in breast cancer (BC) cases and if altered whether delta desaturase activities differ among BC genotypes.