Open AccessRadioprotective effect of grape seed extract against gamma irradiation in mouse bone marrow cells
Author(s) -
Reza Ghasemnezhad Targhi,
Amin Banaei,
Valiallah Saba
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_243_17
Subject(s) - bone marrow , micronucleus test , chemistry , irradiation , clastogen , micronucleus , antioxidant , grape seed extract , giemsa stain , biochemistry , microbiology and biotechnology , pharmacology , andrology , toxicity , biology , immunology , pathology , medicine , genetics , physics , alternative medicine , organic chemistry , nuclear physics
Ionizing radiations produce free radicals which are often responsible for DNA damage or cell death. Grape seed extract (GSE) is a natural compound having an antioxidant that protects DNA, lipids, and proteins from free radical damages. In this study, radioprotective effect of the GSE has been investigated in mouse bone marrow cells using micronucleus test.