Open AccessCorrelation between long non-coding RNAs (lncRNAs) H19 expression and trastuzumab resistance in breast cancer
Author(s) -
Zhaohui Sun,
Chi Zhang,
Tiantian Wang,
Peng Shi,
Xin Tian,
Ying Guo
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_208_19
Subject(s) - trastuzumab , breast cancer , skbr3 , medicine , oncology , cancer research , downregulation and upregulation , biomarker , carcinogenesis , cancer , biology , gene , human breast , biochemistry
Trastuzumab resistance is a major obstacle encountered in human epidermal growth factor receptor 2 (HER2)-positive breast cancer therapy. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in both tumorigenesis and tumor development. However, whether lncRNAs are associated with trastuzumab resistance is not yet clear.