Open AccessIncreased skin reactions with hydroxychloroquine during breast radiotherapy
Author(s) -
HalilCumhur Yildirim,
Musa Şahın,
Burhan Engın,
DidemÇolpan Öksüz
Publication year - 2022
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_145_21
Subject(s) - hydroxychloroquine , medicine , breast cancer , radiation therapy , radiosensitizer , dermatology , adverse effect , skin reaction , chloroquine , oncology , surgery , cancer , pathology , disease , covid-19 , malaria , infectious disease (medical specialty)
With the advances in radiation technology, skin reaction due to postoperative radiotherapy (RT) in breast cancer patients is generally mild and tolerable. However, certain drugs may increase the radiation effect. In literature, only few cases of adverse reactions in the radiation field have been reported with the use of Chloroquine. This report describes the case of a 30-year-old young female who had enhanced skin reactions with hydroxychloroquine (HCQ) treatment during breast RT. HCQ should be used with caution in patients undergoing RT due to its potential radiosensitizer effect.