Open AccessOrientin mitigates 1, 2-dimethylhydrazine induced lipid peroxidation, antioxidant and biotransforming bacterial enzyme alterations in experimental rats
Author(s) -
Kalaiyarasu Thangaraj,
Karthi Natesan,
Kandakumar Settu,
Mariyappan Palani,
Mydhili Govindarasu,
Vanitha Subborayan,
Manju Vaiyapuri
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_1363_16
Subject(s) - orientin , lipid peroxidation , pharmacology , 1,2 dimethylhydrazine , antioxidant , chemistry , biochemistry , colorectal cancer , vitexin , medicine , cancer , flavonoid , dimethylhydrazine
Colorectal cancer (CRC) is the second most diagnosed cancer often identified during the later stages of carcinogenesis. Orientin, a C-glycoside of luteolin, is well known for its versatile therapeutic action toward oxidative stress-induced cellular response may exert chemoprevention against CRC.