Open AccessAssociation of clinicopathological features with E-cadherin (CDH1) gene-160 C>A promoter polymorphism in Turkish colorectal cancer patients
Author(s) -
Anzel Bahadır,
Gökalp Eral,
Metin Budak,
Fumio Shimamoto,
Mehmet Ali Körpınar,
Sibel Erdamar,
Handan Tuncel
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_1277_16
Subject(s) - colorectal cancer , cdh1 , genotype , medicine , allele , gastroenterology , oncology , gene , biology , cancer , genetics , cadherin , cell
The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC in the Turkish patients. To our knowledge, this is the first report examining the role of CDH1 polymorphism in Turkish CRC patients.