Open AccessImmunosuppressive effects and mechanisms of three myeloid-derived suppressor cells subsets including monocytic-myeloid-derived suppressor cells, granulocytic-myeloid-derived suppressor cells, and immature-myeloid-derived suppressor cells
Author(s) -
Yoshiaki Nagatani,
Yohei Funakoshi,
Hironobu Suto,
Yoshiaki Imamura,
Masanori Toyoda,
Naomi Kiyota,
Kimihiro Yamashita,
Hironobu Minami
Publication year - 2021
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_1222_20
Subject(s) - myeloid derived suppressor cell , immunology , immune system , population , t cell , myeloid , cancer research , chemistry , suppressor , cancer , medicine , environmental health
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immune cells of myeloid lineage. Recent reports have suggested that human MDSC are divided into three subsets: monocytic MDSC (M-MDSC), granulocytic MDSC (G-MDSC), and immature MDSC (I-MDSC). However, the characteristics of each human MDSC subset still remain unclear.