Open AccessPrimary leiomyosarcoma kidney – A rare entity with a diagnostic challenge
Author(s) -
Shramana Mandal,
Dimple Chaudhary,
Ashutosh Rath,
Nita Khurana,
PN Agarwal
Publication year - 2022
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_107_19
Subject(s) - leiomyosarcoma , immunohistochemistry , differential diagnosis , renal cell carcinoma , pathology , medicine , kidney , sarcoma
Primary leiomyosarcoma kidney is a rare tumor with an aggressive nature. Leiomyosarcoma is one of the common histologic types of the sarcomas, comprising 60% of all sarcomas. Sarcomatoid renal cell carcinoma is a close differential of renal leiomyosarcoma as both tumors have spindle-shaped cells. The former has a more pleomorphic character with nuclear grade four, which can be differentiated on the basis of immunohistochemistry. Hence, the diagnosis of primary renal leiomyosarcoma poses a diagnostic challenge. One such case of renal leiomyosarcoma in a 45-year-old male is being discussed here.