Open Access125I seeds implantation for an elderly patient of skin squamous cell carcinomas with ulcer guided by ultrasound
Author(s) -
Yaru Liang,
Xuemin Di,
Zezhou Liu,
Jing Zhao,
Zeyang Wang,
Jing Zhao,
Aixia Sui,
Hongtao Zhang,
Juan Wang
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_1032_17
Subject(s) - medicine , brachytherapy , malignancy , concomitant , basal cell , head and neck , radiation therapy , radiology , ultrasound , surgery , dermatology
The skin squamous cell carcinoma (SCC) is a kind of malignancy of keratinocytes. SCC was originated within the epidermis or relevant appendages, which commonly occurred on sunlight exposure sites, such as the head and neck. This case report described an 85-year-old female patient with skin SCC at the right frontal, accompanied with skin ulcer. This patient suffered from indications that were not suitable for surgical resection, including old age, Alzheimer's disease (AD), lacunar infarction, hydropericardium, and some other concomitant diseases. In addition, the external beam radiotherapy was rejected by the relatives of this patient. Then, the patient received 125 I seeds interstitial brachytherapy guided by bedside ultrasound. The tumor response was evaluated based on the response evaluation criteria in solid tumors version 1.1 criteria. Complete response was achieved 4 months after brachytherapy. No complications and recurrence were observed during 8-month follow-up. As the sole modality, the 125 I seeds implantation could be a reasonable and safe alternative for treating skin SCC with ulcer, especially for the elderly patients.