Open AccessMalignant peripheral nerve sheath tumor of the parapharyngeal space arising from cervical sympathetic chain
Author(s) -
Roshan Verma,
Vimmi Gautam,
Amit Bahl,
Amanjeet Bal
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_1005_17
Subject(s) - parapharyngeal space , medicine , neurofibromatosis , magnetic resonance imaging , malignant peripheral nerve sheath tumor , histopathological examination , ptosis , anatomy , cervical ganglia , pathology , radiology , surgery
Malignant peripheral nerve sheath tumors (MPNSTs) of parapharyngeal space are rare and if present are most often in association with neurofibromatosis type 1 (NF-1). Only a few cases of MPNST have been reported in the literature without coexisting NF. We report one such case of an MPNST of parapharyngeal space tumor in a 35-year-old female with no associated features of NF-1. She presented with right-sided neck swelling and ptosis. Magnetic resonance imaging showed a 7 cm × 8 cm × 11 cm irregular swelling in the right parapharyngeal space with invasion of surrounding muscles. The mass was excised using a transcervical approach. Postoperative histopathological examination of the specimen revealed MPNST possibly arising from the cervical sympathetic chain.