Open AccessAntibacterial activity of high-molecular-weight and low-molecular-weight chitosan upon oral pathogens
Author(s) -
Zeinab Abedian,
Niloofar Jenabian,
Ali Akbar Moghadamnia,
Ebrahim Zabihi,
Hamed Tashakorian,
Ramazan Rajabnia,
Farahnaz Sadighian,
Ali Bijani
Publication year - 2019
Publication title -
journal of conservative dentistry/journal of conservative dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 31
eISSN - 0974-5203
pISSN - 0972-0707
DOI - 10.4103/jcd.jcd_300_18
Subject(s) - streptococcus sobrinus , chitosan , streptococcus mutans , antimicrobial , biofilm , microbiology and biotechnology , chitin , chemistry , minimum inhibitory concentration , polysaccharide , minimum bactericidal concentration , food science , bacteria , biology , biochemistry , genetics
One of the common oral bacterial infectious diseases is dental caries. Control of dental plaque formed by Streptococcus mutans and Streptococcus sobrinus leads to prevention and treatment of caries. Chitosan (1-4, 2-amino-2-deoxy-b-D-glucan), a deacetylated derivative from chitin, is an antimicrobial polysaccharide that exerts broad-spectrum activity against pathogenic bacteria and has been suggested as a preventive and therapeutic material for dental caries.