Open AccessA rare case of nasal glial heterotopia in an infant
Author(s) -
Karishma Tahlan,
Nadeem Tanveer,
Harresh Kumar,
Himanshi Diwan
Publication year - 2020
Publication title -
journal of cutaneous and aesthetic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.44
H-Index - 13
eISSN - 0974-5157
pISSN - 0974-2077
DOI - 10.4103/jcas.jcas_148_19
Subject(s) - glial fibrillary acidic protein , medicine , pathology , heterotopia (medicine) , nose , immunohistochemistry , lesion , trichrome stain , stain , anatomy , staining
Glial heterotopias are the displacement of neuroglial tissue in extracranial sites. Nasal glial heterotopias can be of three types-extranasal, intranasal and mixed. Root of the nose is the most common location. These are rare anomalies with an incidence of 1 case in 20,000-40,000 live births. Here we report the case of a 6-month-old infant with a congenital mass located at the root of the nose. Non-contrast computed tomography studies showed no evidence of intracranial communication of the lesion. The mass was excised, and on histopathological examination, it showed glial tissue with astrocytes in a fibrillary background and fibroconnective tissue. Masson's trichrome stain showed the red staining of the glial tissue, whereas the background fibrosis was stained blue. On immunohistochemistry, glial fibrillary acidic protein was positive. Hence, the diagnosis of nasal glial heterotropia was made. The patient had an uneventful postoperative period.