Open AccessGlobal, regional, and national prevalence of depression among cancer patients: A systematic review and meta-analysis
Author(s) -
Ahmad Ghashghaee,
ZahraNoorani Mejareh,
Bahare Abdollahi,
Zahra Hoseinipalangi,
MelikaShamsian Jeze,
Hossein Hosseinifard,
Sima Rafiei,
Farnaz Aghajani,
Afsaneh Dehnad,
MohadesehFadavi Ardakani,
Saba Ahmadi,
Haniyeh Anbarhassani,
M. Morraveggi Asl,
FatemehPashazadeh Kan,
Aidin Aryankhesal,
Hosein Shabaninejad,
Sepideh Aghalou
Publication year - 2021
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/indianjpsychiatry.indianjpsychiatry_77_21
Subject(s) - depression (economics) , medicine , meta analysis , confidence interval , scopus , cancer , colorectal cancer , web of science , medline , political science , law , economics , macroeconomics
This systematic review and meta-analysis aimed to provide a summary of the existing evidence on the prevalence of depression among cancer patients worldwide to assist health policymakers in adopting appropriate measures to prevent and control depression in these patients. EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were searched for original studies published in English from January 2000 to July 2019. The studies were screened on the basis of quality and relevance criteria. The statistical analyses were conducted in the R software. Out of 182,521 cancer patients examined in 183 studies, 49,280 (~27%) had depression (95% confidence interval [CI] = 24%-30%). The highest prevalence of depression was among patients with colorectal cancer with 32% (95% CI = 20%-47%). Among countries, Pakistan with 43% (95% CI = 26%-64%), and among continents, Africa with 36% (95% CI = 29%-43%) had the highest prevalence of reported depression in cancer patients. Adjusting for sample size, the prevalence of depression among female cancer patients, 31% (95% CI = 26%-36%), was higher than men, 26% (95% CI = 21%-31%). The prevalence of depression among cancer patients is increasing by an average of 0.6% per year. The findings show higher prevalence of depression among cancer patients in underdeveloped and developing countries compared to the developed nations and the global average.