Open AccessEvaluation of systemic oxidative stress in patients with premature canities and correlation of severity of hair graying with the degree of redox imbalance
Author(s) -
Snigdha Saxena,
R. K. Gautam,
Aastha Gupta,
Anubhuti Chitkara
Publication year - 2020
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/ijt.ijt_99_19
Subject(s) - oxidative stress , malondialdehyde , medicine , superoxide dismutase , premature aging , reactive oxygen species , physiology , antioxidant , glutathione , endocrinology , biochemistry , biology , enzyme
Premature canities etiopathogenesis is unclear, and approach to its therapy remains arbitrary. Reactive oxygen species generated during melanin biosynthesis in anagen hair bulb have been implicated in melanocyte apoptosis and hair graying. Extraneous factors, namely environmental pollution, stressful lifestyle, may compound the melanogenesis-induced endogenous oxidative stress.