Open AccessPresence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium
Author(s) -
Shane Grace,
Angela Sutton,
Nina F. Abraham,
Eric S. Armbrecht,
C Vidal
Publication year - 2017
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/ijt.ijt_43_16
Subject(s) - tryptase , giemsa stain , mast cell , degranulation , alopecia areata , medicine , scalp , hair loss , skin biopsy , biopsy , pathology , pathogenesis , hair follicle , immunology , dermatology , receptor
Telogen effluvium (TE) is a type of acquired, diffuse alopecia that occurs due to an abnormal shift of scalp hair follicles from anagen to telogen, leading to premature shedding of hair. Previous studies have suggested the existence of a neuroimmunologic "brain-hair follicle" axis, in which mast cells have been implicated as an important link between the nervous system and immunologic system.