Open AccessCytomegalovirus retinitis associated with high CD4 counts and DHEA abuse
Author(s) -
Gan Yuen Keat,
Syed Shoeb Ahmad,
Suresh Subramaniam,
Shuaibah Abdul Ghani,
Amir Samsudin
Publication year - 2020
Publication title -
indian journal of sexually transmitted diseases and aids
Language(s) - English
Resource type - Journals
eISSN - 2589-0565
pISSN - 2589-0557
DOI - 10.4103/ijstd.ijstd_90_15
Subject(s) - cytomegalovirus retinitis , medicine , dehydroepiandrosterone , cytomegalovirus , blindness , human immunodeficiency virus (hiv) , pediatrics , retinitis , immunology , human cytomegalovirus , viral disease , herpesviridae , virus , optometry , androgen , hormone
The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm 3 . Our case report documents an AIDS patient who developed CMVR despite CD4 counts being persistently >200/mm 3 . The patient was self-administering dehydroepiandrosterone, high dose Vitamin C, testosterone and hydrocortisone. This case report describes a unique case of pharmacologically induced elevated CD4 counts, which however, did not prevent the development of CMVR in the patient.