Open AccessCurrent review with evolving management strategies in critical limb ischemia
Author(s) -
Arun Sharma
Publication year - 2019
Publication title -
indian journal of radiology and imaging - new series/indian journal of radiology and imaging/indian journal of radiology and imaging
Language(s) - English
Resource type - Journals
eISSN - 0971-3026
pISSN - 0970-2016
DOI - 10.4103/ijri.ijri_208_19
Subject(s) - medicine , critical limb ischemia , psychological intervention , intensive care medicine , disease , arterial disease , quality of life (healthcare) , ischemia , limb ischemia , vascular disease , surgery , nursing , psychiatry
Critical limb ischemia represents the end stage of peripheral artery disease, which is associated with impaired quality of life and considerable morbidity and mortality. Economical impact of the disease is huge with a substantial burden on patients, healthcare providers, and resources. Varied therapeutic strategies have been employed in the management of these patients. These patients usually have complex multilevel occlusive arteriopathy with significant comorbidities, rendering surgical interventions undesirable in many cases. Recent therapeutic advances with evolving endovascular techniques and gene or cell-based therapies have the potential to dramatically change the therapeutic outlook in these patients.