Open AccessUtility of cell block as an adjunct to liquid-based cytology for diagnosing papillary thyroid carcinoma
Author(s) -
Yun-An Chen,
Ying-Ching Lai,
ShuJiuan Lin,
Cheng-Kuang Yang
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_999_19
Subject(s) - medicine , thyroid carcinoma , thyroid , cytology , pathology , liquid based cytology , calcification , radiology , cancer , cervical cancer
Although liquid-based cytology (LBC) has gained popularity among clinical laboratories, it is unclear whether it is equivalent to conventional smears for making a definite diagnosis of papillary thyroid carcinoma (PTC). The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) suggests a definite diagnosis of PTC is preferred when there are at least one of three features (papillary architecture, psammomatous calcifications, and frequent pseudonuclear inclusions) plus other typical cytomorphological findings. This study evaluated whether an additional cell block (CB), prepared from the residual LBC material, could help improve the diagnosis of PTC.