Open AccessLoss of YY1 expression predicts unfavorable prognosis in stage III colorectal cancer
Author(s) -
Hyunsung Kim,
Seongsik Bang,
Seungyun Jee,
Seongeon Park,
Yeseul Kim,
Hosub Park,
Kiseok Jang,
Seung Sam Paik
Publication year - 2021
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_96_20
Subject(s) - colorectal cancer , cancer , stage (stratigraphy) , tissue microarray , medicine , yy1 , oncology , immunohistochemistry , survival analysis , cancer research , tumor progression , pathology , gene expression , biology , gene , promoter , genetics , paleontology
Yin Yang 1 (YY1), the multifunctional transcription factor, has recently been assigned biological properties related to human malignancies. YY1 can facilitate both tumor suppression and tumor growth. The conflicting role of YY1 in human malignancies is not yet fully explained.