Open AccessRole of platelet aggregation in metastatic breast cancer patients
Author(s) -
Tanisha Singla,
Gaurav Singla,
Sunil Ranga,
Swati Singla,
Rashmi Arora
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_817_19
Subject(s) - breast cancer , medicine , metastatic breast cancer , metastasis , platelet , cancer , oncology , thrombin , ca15 3 , pathology
Breast cancer is the most common female cancer in the world. Although early detection and systematic adjuvant therapy has improved survival, distant metastasis remains the leading cause of breast related mortality. The relationship between tumor and the hemostatic system is increasingly recognized as an important regulator of breast cancer progression. Tumors have the ability to induce platelet aggregation which is referred as tumor cell induced platelet aggregation (TCIPA). This study highlights that increased platelet aggregation plays an important role in metastasis of breast cancer. The aim here is to study the role of platelet aggregation in metastatic breast cancer patients using: • ADP • Thrombin.