Open AccessDiagnostic utility of multiple site duodenal biopsies in celiac disease
Author(s) -
Vikarm Narang,
Akriti Jindal,
Aminder Singh,
Bhavna Mehta,
Neena Sood,
Ajit Sood
Publication year - 2021
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_797_20
Subject(s) - medicine , duodenal bulb , biopsy , gastroenterology , grading (engineering) , diarrhea , pathology , duodenum , biology , ecology
Celiac Disease involves the small intestine patchily affecting more frequently the proximal small bowel but the histological changes have been observed till terminal ileum. Of late in addition to D2, the duodenal bulb (D1 region) biopsies have been found helpful in identifying a small group of patients with CD. Therefore, multiple site biopsies are recommended as histological changes are not uniform throughout small intestine.