Open AccessComparison of lymphangiogenesis, lymphatic invasion, and axillary lymph node metastasis in breast carcinoma
Author(s) -
Prerna Guleria,
V. Srinivas,
D.R. Basannar,
Vibha Dutta
Publication year - 2018
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_774_16
Subject(s) - lymphangiogenesis , lymphatic system , medicine , pathology , lymph node , immunohistochemistry , lymphatic endothelium , lymphatic vessel , breast carcinoma , context (archaeology) , breast cancer , h&e stain , metastasis , cancer , biology , paleontology
Lymphangiogenesis correlates with poor prognosis in Invasive Ductal Carcinoma (IDC) breast. D2-40 antibody, a specific marker for lymphatic endothelium, differentiates lymphatic from vascular endothelium. Therefore, the aims of this study were to estimate lymphangiogenesis using D2-40 antibody and correlate with lymphatic invasion (LI) and axillary lymph node (LN) status and compare lymphatic mean vessel density (LMVD) with Tumor (T) and Node (N) stages and grade of tumor.