Open AccessDuodenal mucosal immune cells in treatment-naive adult patients with celiac disease having different histological grades and controls
Author(s) -
Gaurav Pratap Singh Gahlot,
Prasenjit Das,
Vandana Baloda,
Alka Singh,
Sreenivas Vishnubhatla,
Siddhartha Datta Gupta,
Govind Makharia
Publication year - 2019
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_703_18
Subject(s) - lamina propria , foxp3 , intraepithelial lymphocyte , cd20 , cd8 , cd3 , immune system , immunology , pathology , immunohistochemistry , medicine , biology , epithelium
It is hypothesized that the duodenal mucosal damage in patients with celiac disease (CeD) is caused by the mucosa-infiltrating lymphoid cells. This study aimed to analyze the immune effective and regulatory T (Treg) cells in duodenal biopsies from treatment-naive adult patients with CeD having different histological grades and controls.