Role of ERCC1 expression in colorectal adenoma-carcinoma sequence and relation to other mismatch repair proteins expression, clinicopathological features and prognosis in mucinous and non-mucinous colorectal carcinoma | Zendy

AbdAlRahman Mohammad Foda | Zendy; Andrea Palicelli | Zendy; Abdelhadi M. Shebl | Zendy; Renzo Boldorini | Zendy; Khaled Elnaghi | Zendy; AmiraK El-Hawary | Zendy

Open Access

Role of ERCC1 expression in colorectal adenoma-carcinoma sequence and relation to other mismatch repair proteins expression, clinicopathological features and prognosis in mucinous and non-mucinous colorectal carcinoma

Author(s) -

AbdAlRahman Mohammad Foda,

Andrea Palicelli,

Abdelhadi M. Shebl,

Renzo Boldorini,

Khaled Elnaghi,

AmiraK El-Hawary

Publication year - 2019

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_684_18

Subject(s) - mucinous carcinoma , colorectal adenoma , ercc1 , colorectal cancer , adenoma , medicine , carcinoma , oncology , cancer research , adenocarcinoma , biology , cancer , gene , dna repair , biochemistry , nucleotide excision repair

There are several DNA repair pathways that protect cellular DNA from injury, such as nucleotide excision repair (NER) and mismatch repair (MMR). The protein product of the excision repair cross-complementation group 1 (ERCC1) gene plays a pivotal role in NER. The exact relationship between MMR proteins and ERCC1 is not well known in colorectal carcinoma (CRC).

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