Evaluation of CD30/CD4/CD8 in triple-negative invasive ductal carcinoma of breast in association with clinicopathological prognostic factors | Zendy

Nema Mohamadian Roshan | Zendy; Amir Hossein Jafarian | Zendy; Aida Tasbandi | Zendy; Hamed Gilan | Zendy; Maryam Sheikhi | Zendy

Open Access

Evaluation of CD30/CD4/CD8 in triple-negative invasive ductal carcinoma of breast in association with clinicopathological prognostic factors

Author(s) -

Nema Mohamadian Roshan,

Amir Hossein Jafarian,

Aida Tasbandi,

Hamed Gilan,

Maryam Sheikhi

Publication year - 2018

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_67_18

Subject(s) - breast cancer , immunohistochemistry , medicine , cd8 , oncology , stage (stratigraphy) , lymph node , cd30 , lymph , triple negative breast cancer , pathology , cancer , biology , immunology , antigen , paleontology

Triple-negative breast cancer (TNBC) lacks the benefits of receptor-targeted therapeutic strategies. The limitations in treatment options along with poor patients' outcome heighten the need for novel approaches. Due to recent concentration on the role of biomarkers in prognosis, treatment, and survival of various cancer subtypes, this study involves an investigation of CD4, CD8, and CD30 markers detected by immunohistochemistry in TNBCs and their association with clinicopathological and prognostic factors.

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