Open AccessAssessment of apoptotic index in various grades of oral epithelial dysplasia: A cross-sectional study
Author(s) -
Rasika Pawar,
Sangeeta Palaskar,
Shravani S Kalavankar
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_565_19
Subject(s) - dysplasia , apoptosis , epithelial dysplasia , medicine , pathology , cancer , proliferation index , oncology , cancer research , immunohistochemistry , biology , genetics
: Oral cancer is a major health problem worldwide. In cancer, the equilibrium between cell proliferation and apoptosis is disturbed. The defect in the apoptotic pathway allows cells to proliferate with genetic abnormalities. Thus, the apoptotic index (AI) can be used to assess the significance of apoptosis as a proliferative marker in oral epithelial dysplasia.