Evaluation of the presence of myofibroblasts and matrix metalloproteinase 1 expression in the stroma of oral verrucous hyperplasia and verrucous carcinoma | Zendy

Merva Soluk Tekkeşin | Zendy; Nazanin Mahdavi | Zendy; Pouyan Aminishakib | Zendy; Parisa Nabiyi | Zendy; Alireza Ghanadan | Zendy; Maedeh Ghorbanpour | Zendy

Open Access

Evaluation of the presence of myofibroblasts and matrix metalloproteinase 1 expression in the stroma of oral verrucous hyperplasia and verrucous carcinoma

Author(s) -

Merva Soluk Tekkeşin,

Nazanin Mahdavi,

Pouyan Aminishakib,

Parisa Nabiyi,

Alireza Ghanadan,

Maedeh Ghorbanpour

Publication year - 2020

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_548_19

Subject(s) - verrucous carcinoma , stromal cell , immunohistochemistry , pathology , stroma , myofibroblast , medicine , matrix metalloproteinase , proliferation index , carcinoma , cancer research , fibrosis

Oral verrucous carcinoma is a low-grade subtype of oral squamous cell carcinoma that should be differentiated from oral verrucous hyperplasia, a premalignant lesion. Stromal activated myofibroblasts known as cancer-associated fibroblasts have an active role in the initiation and progression of the cancers via secretion of different molecules including matrix metalloproteinases.

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