Open AccessEpidermal growth factor receptor and anaplastic lymphoma kinase mutation in adenocarcinoma lung: Their incidence and correlation with histologic patterns
Author(s) -
Pankaj Gupta,
Swarnalata Gowrishankar,
Meenakshi Swain
Publication year - 2019
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_516_16
Subject(s) - epidermal growth factor receptor , adenocarcinoma , anaplastic lymphoma kinase , immunohistochemistry , pathology , lung cancer , biology , biopsy , population , lung , cancer research , medicine , cancer , environmental health , malignant pleural effusion
Epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) mutational analysis in adenocarcinoma lung are growing in importance as these tests are essential in guiding the use of targeted therapy. However, the prevalence of these mutations in various populations in India has not been studied. Furthermore, the correlation of histologic pattern with the mutation is not clear.