Open AccessExpression of α-smooth muscle actin in benign and malignant salivary gland tumors: An immunohistochemical study
Author(s) -
Mahalakshmi Ravi,
Karen Boaz,
Srikant Natarajan,
Amitha J Lewis,
Mukul Prasad,
Swetha Yellapurkar
Publication year - 2018
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_482_17
Subject(s) - immunohistochemistry , salivary gland , pathology , actin , smooth muscle , medicine , anatomy , biology , microbiology and biotechnology
Myoepithelial cells (ME) are known to contribute in the patterning of salivary gland neoplasms (SGN) and possess cytoplasmic smooth muscle actin (SMA) revealed by alpha SMA (α-SMA). The present study aimed to assess the expression of α-SMA in selected benign and malignant SGN (pleomorphic adenoma [PA], mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC), and polymorphous low-grade adenocarcinoma (PLGA).