Expression of α-smooth muscle actin in benign and malignant salivary gland tumors: An immunohistochemical study | Zendy

Karen Boaz | Zendy; Mahalakshmi Ravi | Zendy; Srikant Natarajan | Zendy; Amitha J Lewis | Zendy; Mukul Prasad | Zendy; Swetha Yellapurkar | Zendy

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Expression of α-smooth muscle actin in benign and malignant salivary gland tumors: An immunohistochemical study

Author(s) -

Karen Boaz,

Mahalakshmi Ravi,

Srikant Natarajan,

Amitha J Lewis,

Mukul Prasad,

Swetha Yellapurkar

Publication year - 2018

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_482_17

Subject(s) - myoepithelial cell , sma* , pathology , adenoid cystic carcinoma , immunohistochemistry , stroma , adenocarcinoma , biology , salivary gland , carcinoma , cancer , chemistry , medicine , mathematics , combinatorics , genetics

Myoepithelial cells (ME) are known to contribute in the patterning of salivary gland neoplasms (SGN) and possess cytoplasmic smooth muscle actin (SMA) revealed by alpha SMA (α-SMA). The present study aimed to assess the expression of α-SMA in selected benign and malignant SGN (pleomorphic adenoma [PA], mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC), and polymorphous low-grade adenocarcinoma (PLGA).

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