Open AccessC-cell hyperplasia in sporadic and familial medullary thyroid carcinoma
Author(s) -
Mahima Yadav,
Vinita Agrawal,
K. C. Pani,
Ritu Verma,
Sushila Jaiswal,
Anjali Mishra,
Rakesh Pandey
Publication year - 2018
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_478_17
Subject(s) - medicine , calcitonin , medullary carcinoma , hyperplasia , thyroid , thyroid carcinoma , immunohistochemistry , medullary cavity , pathology , gastroenterology
C-cell hyperplasia (CCH) is characterized by increased mass of C-cells and has been identified as a precursor condition for medullary thyroid carcinoma (MTC). Varying proportion of MTCs is associated with CCH in different studies. This could be due to the lack of uniformity of the definitions and techniques used to identify CCH in these studies.