Open AccessImmunohistochemical expression of interlukin10 (IL10) and heat shock protein-90 (HSP-90) in prostatic carcinoma
Author(s) -
Wasan A. Bakir,
Hiba Ahmed Gaidan,
Methaq Mueen Al-Kaabi
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_460_19
Subject(s) - prostate , medicine , immunohistochemistry , carcinoma , grading (engineering) , pathology , hyperplasia , interleukin 10 , pathological , cytokine , biology , cancer , ecology
Specific cytokines are related to pathologically changed prostate, propose that the balance in cytokine differs in normal and pathological prostate. Of these cytokines the interleukins 10, due to its "pleiotropic" actions in inflammation and angiogenesis, and HSP-90 due to its expression in tumor cells at high levels, suggesting that it has an important role for growth and/or survival of tumor cells.