Association of different patterns of expression of beta-catenin and cyclin D1 with pathogenesis of breast carcinoma | Zendy

Kachnar Varma | Zendy; Aprajita Chauhan | Zendy; Mudita Bhargava | Zendy; Vatsala Misra | Zendy; Sapan Srivastava | Zendy

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Association of different patterns of expression of beta-catenin and cyclin D1 with pathogenesis of breast carcinoma

Author(s) -

Kachnar Varma,

Aprajita Chauhan,

Mudita Bhargava,

Vatsala Misra,

Sapan Srivastava

Publication year - 2020

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_419_19

Subject(s) - cyclin d1 , wnt signaling pathway , cancer research , immunohistochemistry , carcinogenesis , breast cancer , beta catenin , cancer , cyclin , catenin , breast carcinoma , biology , oncology , medicine , pathology , cell cycle , gene , genetics

Beta-catenin and cyclin D1 have attracted considerable attention in recent studies as potential proto-oncogenes in many human cancers especially colonic cancer. Beta-catenin plays multiple roles within the cell such as canonical Wnt signaling where cyclin D1 has been identified as one of its target genes. The role of beta-catenin and cyclin D1 in breast cancer has been evaluated in many studies but not established yet.

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