
Keratomycosis due to Purpureocillium lilacinum: A case report from Sub-Himalayan region of Uttarakhand
Author(s) -
Deepak Juyal,
Sarika Pal,
Munesh Sharma,
Vikrant Negi,
Shamanth Adekhandi,
Manoj Tyagi
Publication year - 2018
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_404_17
Subject(s) - voriconazole , fungus , antifungal , fungal pathogen , pathogen , microbiology and biotechnology , medicine , biology , botany
The fungus Purpureocillium lilacinum previously known as Paceliomyces lilacinus is an emerging pathogen that can cause severe human infections including devastating oculomycosis. Treatment with traditional antifungals often fails, and the organism shows variable susceptibility to novel triazoles. We hereby report a case of keratomycosis caused by Pur. lilacinum in an immunocompetent male patient following trauma. The patient was successfully treated with voriconazole. The drug shows good activity against Pur. lilacinum and could be a promising therapeutic alternative to treat infections caused by this fungus, which generally shows resistance to conventional antifungal agents including novel triazoles.