Open AccessVascular endothelial growth factor expression in placenta of hypertensive disorder in pregnancy
Author(s) -
Abd Fuaat Azliana,
Mohamad Razi Zainul-Rashid,
Sabrina Florence Chandramaya,
Wirda Indah Farouk,
Nurwardah Alfian,
Yin Ping Wong,
Geok Chin Tan
Publication year - 2017
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_376_16
Subject(s) - syncytiotrophoblasts , placenta , vascular endothelial growth factor , medicine , pregnancy , immunohistochemistry , fetus , endocrinology , obstetrics , andrology , vegf receptors , biology , genetics
Hypertensive disorder in pregnancy (HDP) represents the most common medical complication in pregnancy. It is the leading cause of maternal and perinatal mortality and morbidity. Vascular endothelial growth factor (VEGF) stimulates vascular endothelial cell growth, survival, and proliferation, and they are known to be expressed in human placenta. The aim of this study was to determine the VEGF expression in the placenta of hypertensive and normotensive patients.