Open AccessMultiple intracranial cryptococcomas in an immunocompetent patient with pulmonary involvement
Author(s) -
Sarojini Raman,
Nilanjan Mukherjee,
Kanakalata Dash,
Kamal Sen
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_331_19
Subject(s) - medicine , cryptococcosis , central nervous system , presentation (obstetrics) , case fatality rate , cryptococcal meningitis , lung , human immunodeficiency virus (hiv) , meningitis , immunology , pathology , pediatrics , epidemiology , surgery , viral disease
Opportunistic infections affecting central nervous system (CNS) have high prevalence in developing countries and cryptococcosis is one of them. It is associated with myriad of signs symptoms and clinical behavior. Though commonly associated with AIDS/HIV infection, it has been reported to be pathogenic in immunocompetent patients. Leptomeningitis is most common presentation in CNS, but unusual tumor like mass lesions have been reported. Lungs are primary site of infection, but it can affect different organs with varied clinical presentations. Therefore, correct diagnosis and proper management is essential in such cases excluding the differentials as fatality rate can be quite high. We report such an unusual case of multiple cryptococcal mass lesions in brain in a healthy immune competent individual with bilateral pulmonary involvement.