Open AccessA prospective study of association of cancer stem cell marker aldehyde dehydrogenase 1 with clinicopathological profile in lung carcinoma patients
Author(s) -
Neema Tiwari,
Anand Srivastava,
Nishi Tandon,
Nirupma Lal,
Shailendra Kumar Yadav,
Surya Kant,
Manoj Jain
Publication year - 2018
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_318_17
Subject(s) - aldehyde dehydrogenase , lung cancer , medicine , prospective cohort study , oncology , carcinoma , pathology , lung , cancer stem cell , cancer , biology , gene , genetics
In India, lung carcinoma is the fifth-most common tumor and second-most common tumor in the males as per the Indian Council of Medical Research registry of 2002. It has been seen that ALDH1 expression in non-small cell lung cancer (NSCLC) and the presence of marker was linked to a more tumorigenic potential in the in vivo assessment and shorter disease-free survival in NSCLC patients with platinum treatment.