Anaplastic Lymphoma Kinase positive large B cell lymphoma of ileocaecal mesentery: A case report | Zendy

Divya Gnanasekaran | Zendy; Aravinth Subramaniam | Zendy; Saravanakumar Suruliraj | Zendy; Palanivelu Chinnusamy | Zendy

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Anaplastic Lymphoma Kinase positive large B cell lymphoma of ileocaecal mesentery: A case report

Author(s) -

Divya Gnanasekaran,

Aravinth Subramaniam,

Saravanakumar Suruliraj,

Palanivelu Chinnusamy

Publication year - 2020

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/ijpm.ijpm_296_19

Subject(s) - lymphoma , mesentery , diffuse large b cell lymphoma , anaplastic lymphoma kinase , pathology , neoplasm , vimentin , immunohistochemistry , cd43 , b cell lymphoma , medicine , gist , cd20 , malignant pleural effusion , lung cancer , stromal cell

ALK+ large B cell lymphoma (LBCL) is a very rare aggressive neoplasm. It accounts for less than 1% of diffuse large B cell lymphoma (DLBCL). This is a case report of ALK+ DLBCL in a 34-year-old woman with an ileocaecal mesenteric mass. Microscopically, the neoplastic cells were of high grade along with a spindle cell component. Immunohistochemistry revealed ALK+, MUM-1+, LCA+, Vimentin+, EMA+ and negative for CK 20, CK 7, neuroendocrine, melanocytic, muscle specific, and GIST panel markers. This case report, hence, presents the rarity of this tumor.

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