Open AccessAnaplastic Lymphoma Kinase positive large B cell lymphoma of ileocaecal mesentery: A case report
Author(s) -
Aravinth Subramaniam,
Divya Gnanasekaran,
Saravanakumar Suruliraj,
Chinnusamy Palanivelu
Publication year - 2020
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_296_19
Subject(s) - lymphoma , mesentery , anaplastic lymphoma kinase , pathology , diffuse large b cell lymphoma , neoplasm , vimentin , immunohistochemistry , b cell lymphoma , medicine , cd43 , cd20 , malignant pleural effusion , lung cancer
ALK+ large B cell lymphoma (LBCL) is a very rare aggressive neoplasm. It accounts for less than 1% of diffuse large B cell lymphoma (DLBCL). This is a case report of ALK+ DLBCL in a 34-year-old woman with an ileocaecal mesenteric mass. Microscopically, the neoplastic cells were of high grade along with a spindle cell component. Immunohistochemistry revealed ALK+, MUM-1+, LCA+, Vimentin+, EMA+ and negative for CK 20, CK 7, neuroendocrine, melanocytic, muscle specific, and GIST panel markers. This case report, hence, presents the rarity of this tumor.