Open AccessApplicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
Author(s) -
Prasenjit Das,
Lalita Mehra
Publication year - 2021
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_260_21
Subject(s) - gastrointestinal tract , medicine , clinical trial , gastrointestinal cancer , oncology , intensive care medicine , interpretation (philosophy) , pathology , cancer , colorectal cancer , computer science , programming language
The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more trials are being undertaken. However, pathologists often get perplexed by different methods of interpretation and reporting of these stains, vital for deciding therapeutic approaches.