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Spermatocytic seminoma with rhabdomyoblastic differentiation: Case report and review of literature
Author(s) -
ArchanaLaxman Khade,
Vinita Pandey,
Yasmeen Khatib,
Rahul Pandey,
ManishaS Khare
Publication year - 2018
Publication title -
indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/ijpm.ijpm_243_17
Subject(s) - seminoma , germ cell , malignant transformation , pathology , pathological , medicine , biology , chemotherapy , genetics , gene
Spermatocytic seminoma (SCS) is an indolent germ cell tumor of the testis. It has an excellent prognosis and orchidectomy is generally curative. Very rarely, it can be complicated by a sarcomatous transformation which is associated with a very aggressive behavior and requires adjuvant therapy. SCS with sarcomatous component is a very rare occurrence with <20 cases described in the world literature of which eight showed rhabdomyoblastic differentiation. We report a case of SCS with rhabdomyosarcomatous differentiation in a 60-year-old male along with a short review of literature.

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