Open AccessThe evaluation of efficacy and safety of methotrexate and pioglitazone in psoriasis patients: A randomized, open-labeled, active-controlled clinical trial
Author(s) -
Afroz Abidi,
Dilshad Ali Rizvi,
Kshitij Saxena,
Savita Chaudhary,
Ali Ahmad
Publication year - 2020
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_88_19
Subject(s) - pioglitazone , medicine , psoriasis , methotrexate , psoriasis area and severity index , adverse effect , randomized controlled trial , pharmacology , dermatology , diabetes mellitus , type 2 diabetes , endocrinology
Psoriasis is a chronic inflammatory disease showing co-existence with metabolic syndrome (MS), as has been confirmed by numerous epidemiologic studies in recent times. In this study, the aim was to ascertain the beneficial effects of pioglitazone in psoriasis, simultaneously targeting the improvement of MS parameters.