Open AccessTherapeutic potential of diosmin, a citrus flavonoid against arsenic-induced neurotoxicity via suppression of NOX 4 and its subunits
Author(s) -
Rupasree Peruru,
Sujatha Dodoala
Publication year - 2021
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_837_19
Subject(s) - neurotoxicity , sodium arsenite , pharmacology , arsenic , arsenic toxicity , oxidative stress , toxicity , diosmin , chemistry , toxicology , medicine , biology , flavonoid , biochemistry , antioxidant , organic chemistry
Water contaminated with arsenic affected millions of people worldwide and arsenic exposure is related to various neurological disorders. Hence, the current study was planned to investigate the neuroprotective activity of diosmin (DSN) against arsenic induced neurotoxicity as an attempt to identify therapeutic intervention to combat arsenicism.