Open AccessIncreased apoptosis, tumor necrosis factor-α, and DNA damage attenuated by 3',4'-dihydroxyflavonol in rats with brain İschemia-reperfusion
Author(s) -
Dervis Dasdelen,
Merve Solmaz,
Esma Menevşe,
Rasim Moğulkoç,
Abdülkerim Kasım Baltacı,
Ender Erdoğan
Publication year - 2021
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_727_20
Subject(s) - tunel assay , apoptosis , ischemia , tumor necrosis factor alpha , necrosis , medicine , reperfusion injury , endocrinology , terminal deoxynucleotidyl transferase , dna damage , andrology , chemistry , dna , biochemistry
This research was aimed to find out the effects of 3',4'-dihydroxyflavonol (DiOHF) on apoptosis, DNA damage, and tumor necrosis factor-α (TNF-α) levels in the frontal cortex of rats with induced experimental brain ischemi reperfusion.