Open AccessInvestigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach
Author(s) -
Sanjay Kumar Singh,
S. M. Reddy
Publication year - 2019
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_535_19
Subject(s) - biology , nonsynonymous substitution , gene , plasmodium falciparum , computational biology , genetics , single nucleotide polymorphism , dna sequencing , genome , malaria , genotype , immunology
Incidences of resistance to current drugs by Plasmodium is increasing, hence, it is necessary to investigate and explore new drug targets to combat malarial disease.