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Investigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach
Author(s) -
SudhakaraM Reddy,
Sanjay Kumar Singh
Publication year - 2019
Publication title -
indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_535_19
Subject(s) - nonsynonymous substitution , biology , plasmodium falciparum , single nucleotide polymorphism , genetics , dna sequencing , computational biology , gene , malaria , genotype , immunology , genome
Incidences of resistance to current drugs by Plasmodium is increasing, hence, it is necessary to investigate and explore new drug targets to combat malarial disease.

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