Zidovudine-induced lactic acidosis with acute pancreatitis and myopathy: Lethal and rare complications | Zendy

SubodhKumar Mahto | Zendy; PulinKumar Gupta | Zendy; R. Taneja | Zendy; Akanksha Singh | Zendy

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Zidovudine-induced lactic acidosis with acute pancreatitis and myopathy: Lethal and rare complications

Author(s) -

SubodhKumar Mahto,

PulinKumar Gupta,

R. Taneja,

Akanksha Singh

Publication year - 2018

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/ijp.ijp_285_18

Subject(s) - medicine , lactic acidosis , zidovudine , acute pancreatitis , pancreatitis , myopathy , human immunodeficiency virus (hiv) , antiretroviral therapy , intensive care medicine , pediatrics , immunology , viral disease , viral load

Highly active antiretroviral therapy (HAART) is nowadays universally available to patients with HIV/AIDS. This has led to increased longevity in people living with HIV/AIDS. However, these patients frequently face chronic and rarely acute life-threatening complications of HAART. Herein, we report the case of a patient who was on HAART and developed zidovudine-induced lactic acidosis, acute pancreatitis, and myopathy. Although these acute complications are rare, a high index of suspicion is required for early diagnosis and to reduce significant morbidity and mortality.

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