Open AccessZidovudine-induced lactic acidosis with acute pancreatitis and myopathy: Lethal and rare complications
Author(s) -
Subodh Kumar Mahto,
Parakriti Gupta,
Rajesh Taneja,
Akanksha Singh
Publication year - 2018
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_285_18
Subject(s) - medicine , lactic acidosis , zidovudine , acute pancreatitis , pancreatitis , myopathy , human immunodeficiency virus (hiv) , antiretroviral therapy , intensive care medicine , pediatrics , immunology , viral disease , viral load
Highly active antiretroviral therapy (HAART) is nowadays universally available to patients with HIV/AIDS. This has led to increased longevity in people living with HIV/AIDS. However, these patients frequently face chronic and rarely acute life-threatening complications of HAART. Herein, we report the case of a patient who was on HAART and developed zidovudine-induced lactic acidosis, acute pancreatitis, and myopathy. Although these acute complications are rare, a high index of suspicion is required for early diagnosis and to reduce significant morbidity and mortality.