Open AccessEfficacy ratio: A tool to enhance optimal antimicrobial use for intra-abdominal infections
Author(s) -
Priyanka Sabu,
Divyaa Elangovan,
Agila Kumari Pragasam,
Yamuna Devi Bakthavatchalam,
Camilla Rodrigues,
DS Chitnis,
Bhaskar Narayan Chaudhuri,
Balaji Veeraraghavan
Publication year - 2018
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_264_18
Subject(s) - ertapenem , tazobactam , piperacillin , antimicrobial , amikacin , antibiotics , antibiotic resistance , klebsiella pneumoniae , minimum inhibitory concentration , medicine , cefotetan , microbiology and biotechnology , meropenem , biology , escherichia coli , imipenem , bacteria , pseudomonas aeruginosa , gene , biochemistry , genetics
Antimicrobial resistance and inappropriate antibiotic regimen hamper a favorable outcome in intra-abdominal infections. Clinicians rely on the minimum inhibitory concentration (MIC) value to choose from the susceptible antimicrobials. However, the MIC values cannot be directly compared between the different antibiotics because their breakpoints are different. For that reason, efficacy ratio (ER), a ratio of susceptible MIC breakpoint and MIC of isolate, can be used to choose the most appropriate antimicrobial.