Open AccessEffects of clozapine and haloperidol treatment on plasma concentrations of androgen hormones and androgendependent organ changes in rats
Author(s) -
Afshin Samadi,
Selen Yılmaz Işıkhan,
M H Khadem Ansari,
Mahshid Samadi,
Suna Sabuncuoğlu
Publication year - 2019
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_145_18
Subject(s) - haloperidol , clozapine , hormone , endocrinology , androgen , medicine , plasma levels , pharmacology , schizophrenia (object oriented programming) , psychiatry , dopamine
Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of haloperidol and clozapine on testosterone, cortisol, and corticosterone levels and also their influence on androgen-dependent organs in adult male Wistar rats.