Effects of clozapine and haloperidol treatment on plasma concentrations of androgen hormones and androgendependent organ changes in rats | Zendy

Afshin Samadi | Zendy; Selen Yılmaz Işıkhan | Zendy; MohammadHasan Khadem Ansari | Zendy; Mahshid Samadi | Zendy; Suna Sabuncuoğlu | Zendy

Open Access

Effects of clozapine and haloperidol treatment on plasma concentrations of androgen hormones and androgendependent organ changes in rats

Author(s) -

Afshin Samadi,

Selen Yılmaz Işıkhan,

MohammadHasan Khadem Ansari,

Mahshid Samadi,

Suna Sabuncuoğlu

Publication year - 2019

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/ijp.ijp_145_18

Subject(s) - haloperidol , clozapine , testosterone (patch) , endocrinology , medicine , androgen , hormone , corticosterone , antipsychotic , pharmacology , schizophrenia (object oriented programming) , dopamine , psychiatry

Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of haloperidol and clozapine on testosterone, cortisol, and corticosterone levels and also their influence on androgen-dependent organs in adult male Wistar rats.

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