Open AccessInfluence of cytochrome P450 3A5 (CYP3A5) genetic polymorphism on dose-adjusted plasma levels of carbamazepine in epileptic patients in South Indian population
Author(s) -
Mahalakshmi Ganesapandian,
Kesavan Ramasamy,
Adithan Chandrasekaran,
Sunil Narayan
Publication year - 2019
Publication title -
indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_122_19
Subject(s) - carbamazepine , cyp3a5 , genotyping , population , medicine , pharmacology , plasma concentration , polymorphism (computer science) , genotype , epilepsy , gastroenterology , chemistry , biochemistry , environmental health , psychiatry , gene
The aim of the study was to compare the dose-adjusted plasma levels of carbamazepine (CBZ) among expressers and nonexpressers of cytochrome P450 3A5 (CYP3A5)* 3 genotypes.