Open AccessInfluence of cytochrome P450 3A5 (CYP3A5) genetic polymorphism on dose-adjusted plasma levels of carbamazepine in epileptic patients in South Indian population
Author(s) -
Kesavan Ramasamy,
Mahalakshmi Ganesapandian,
C Adithan,
Sunil K. Narayan
Publication year - 2019
Publication title -
indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/ijp.ijp_122_19
Subject(s) - carbamazepine , cyp3a5 , genotyping , population , cyp3a , pharmacology , medicine , plasma concentration , chemistry , genotype , gastroenterology , epilepsy , cytochrome p450 , metabolism , biochemistry , environmental health , psychiatry , gene
The aim of the study was to compare the dose-adjusted plasma levels of carbamazepine (CBZ) among expressers and nonexpressers of cytochrome P450 3A5 (CYP3A5)* 3 genotypes.
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